Quality control is a serious issue for the pharmacological industry since the products affect the public health quiet clearly. Assessing the quality of drugs can be as easy as using these modern technologies.
Impurities and adulterants in raw materials pose potential health threats when present in the manufacturing of pharmaceutical APIs and drug products. These same impurities and adulterants may also result in lower production yields and greater needs for product purification. Thus, their identification and quantification within incoming raw material play an important role in the pharma industry, ensuring product safety & quality, and an overall smooth and cost-efficient manufacturing process.
Incoming goods inspection and quality control using FT-IR spectroscopy are mainly performed using the so-called ATR (Attenuated Total Reflection) technique. It allows measuring IR spectra of almost all types of liquid, solid, and paste-like samples within some seconds. For identity control, the sample spectrum is compared against the spectrum of a reference substance.
The growing demand for portable Raman systems for material verification is constituted in the vast capabilities of this spectroscopic technique. High selective information content and no need for sample preparation combined with the capability to probe materials directly through transparent packaging material often make Raman spectroscopy as the method of choice.
Pharmaceutical drug products or crystallographic samples need some characterization of their particles and some information about the distribution of their compounds (active substances, excipients…). Such characteristics have high influence on the dissolution rate, the bioavailability or the stability of the sample. Thus, it is of great importance to have analytical instrumentations which give such information to insure the quality of the products and also to respect strict regulatory and manufacturing procedures.
Dedicated for industrial raw materials control and identification of unknown substances.
XGT-9000 provides ultimate performance and flexibility with its well-designed excitation system. The X-ray generator has high output up to 50 kV and 1000 µA. In addition, primary X-rays can be irradiated through our wide selection of probe sizes (10 microns – 1.2 mm). This includes ultra-high intensity probes to achieve fast measurement speeds.